Members


WGName SurnamesCountryCityInstitutionCharge Research Line
WG3Agnieszka SirkoPolandWarsawInstitut Of Biochemistry and Biophysics PolishMCT / WG3 VLAbiotic stress, Starvation, Nutrient deficit, Protein-protein interactions, Molecular biology, Ubiquitination.
WG5Alejandro LuciaSpainMadridLaureate - Universidad EuropeaImproved autophagy as a main biological mechanism mediating the health benefits of physical exercise.
WG1Aleksandra IsakovicSerbiaBelgradeUniversity of BelgradeMC S
WG2/WG4Alexander Pintzas Greece Athens National Hellenic Research Foundation “My research interests have been in the scientific areas of Biology of Cancer and Cell Death, towards exploitation of the interplay of proliferative with apoptotic/autophagic pathways for novel cancer therapeutics and their rational combinations”.
WG1Ali KosarTurkeyIstanbulSabanci UniversityEffects of cavitation on autophagy, Flow stresses on autophagy, Bubble collapse effect.
WG1Alicia AlonsoSpainBilbaoUniversidad del País Vasco. CSICPhospholipases and sphingomyelinases, influence of the physical state of the membrane on their enzymatic activity; ceramides, diacylglycerols; GPI-lipids; membrane fusion; lipid polymorphism.
WG3Alisdair FernieGermanyGolmMax Planck GesellschaftAutophagy's role in plant metabolism.
WG2/WG4Ana Vanessa Oliveira Portugal Oeiras Instituto de Biologia Experimental e Tecnológica and Instituto de Tecnologia Química e Biológica (ITQB/UNL) Focused on translational science mainly biochemistry, cellular and molecular biology and its application to the field of gene therapy, development of biopolymers and diabetes. Interested in developing new disease models, including yeast models to complement tests in mammalian cells and animal models involved in the development of new therapeutical strategies.
WG1Anders H.LundDenmarkCopenhagenUniversity of CopenhagenMC TUnveiling fundamental biological mechanisms and understand how these become perturbed during diseases, most prominently cancer, with the ambition to contribute to the development of clinical tools.
WG1/WG4Andrea BallabioItalyPozzuoli TIGEMTo develop tools, to modulate cellular clearance and to use them to cure human diseases, including LSDs and neurodegenerative diseases such as Huntington’s, Alzheimer’s and Parkinson’s.
WG4Andrea CossarizzaItalyModenaUniversity of Modenaand Reggio EmiliaMC S / TC VLImmunopathogenesis of HIV infection; Immunology of Aging; Immunological alterations in Multiple Sclerosis; role of mitochondria in cell death and survival.
WG4AngeloDe MilitoSwedenStockholmKaolinska InstitutMC TIdentify the mechanisms mediating the role of autophagy in cancer cells adaptation to acidosis. Identify effective autophagy inhibitors active on cancer cells adapted to acidosis.
WG3Anna WawrzyńskaPolandWarsawInstitute of Biochemistry and BiophysicsMC S
WG1/WG4Anne SimonsenNorwayOsloUniversity of Oslo-Institut Of Basic Medical ScienceMC T1) Autophagy receptors and adaptors in selective autophagy, 2) Phosphoinositide-binding proteins in autophagy and 3) their role in disease.
WG4Annemarie MeijerNetherlandsLeidenLeiden University Institut of BiologieMC TRole of autophagy in host defense against intracellular bacteial infections. Using zebrafish as a model to study autophagy in vivo and recently found that the autophagy modulator dram1 is induced by Toll-like receptor and NFkB mediated signaling and protects the zebrafish host against mycobacterial infection. Using the zebrafish model for screening of autophagy-modulating drugs.
WG3Antia
Rodriguez-Villalon Switzerland Zurich ETH-ZurichVascular development study in which autophagy has a key role, in particupar in "postmortem" stages.
WG1/WG2/WG4Antonio ZorzanoSpainBarcelonaIRB Barcelona IRB Barcelona, University of Barcelona, CIBERDEMIdentification of novel modulators of autophagy and impact in complex metabolic diseases.
WG2/WG4Antonio CuadradoSpainMadridUniversidad Autónoma de MadridProteostasis alterations of Alzheimer and Parkinson’s disease and the possibility to use autophagy as a therapeutic target.
WG4/WG5Arnaud MorisFranceParisCenter for Immunology and Microbial infections - ParisHost-Pathogen interactions, Adaptive Immunity, Inflammation, Antigen presentation and Vaccine Design.
WG4Audrey EsclatineFranceParisUniversité Paris Sud CNRS-I2BCRelationships between autophagy and viral infection.
WG5Aurelio Hernández LaínSpainMadridHospital Universitario 12 de OctubreClinical trials for patients with cerebral tumors.
WG1Aurelio SerranoSpainSevillaCSIC Instituto de Bioquímica Vegetal y FotosíntesisInterest in the interplay between lumenal acidification and autophagy. Particularly in outline which is the involvement of the different types of proton pumps (H and V-ATPases-pyrophosphatase) in this process. Additionally, interested in physiologically relevant factors affecting the activity of these pumps and how this results in inhibition or induction of autophagy and other effects at the cellular level in model organisms such as yeast, Arabidopsis thaliana, and mammalian cell lines.
WG4Aurore RozièresFranceLyonCSIC-Univ. de Sevilla, Instituto de Bioquímica Vegetal y FotosíntesisAutophagy in Crohn's disease
WG4Bassam JanjiLuxembourgLuxemburgLuxembourg Institut Of HealthMC TInvestigate the role of autophagy in the regulation of the anti-tumor immune response under hypoxic stress.
WG4Beata PajakPolandWarszawaMossakowski Medical Research CentreMC TThe importance of autophagy in neurodegenerative diseases (AD), cancer, as well as metabolic syndrome.
WG5Beata Sikorska Poland Lodz Medical University of LodzOur group is working on autophagy in prion  diseases and neurodegeneration in humans
WG1/WG2/WG4/WG5Benjamin DehayFranceBordeauxIMN-CNRS UMR 5293DC LLysosomal Impairment, Parkinson's disease, Therapeutic approaches.
Boris TurkSloveniaLjubljanaJozef Stefan InstituteMC S
WG3Béatrice Satiat-Jeunemaitre FranceGif sur YvetteInstitut de Biologie Intégrative de la Cellule - CNRSPlant cell biology, Morphodynamics of cell comparment, autophagosome, Endomembranes.
WG4Carlos GuillénSpainMadridUniversidad Complutense de MadridmTORC1, SIRT1, insulin, amylin, aging, resveratrol, diabetes.
WG1Carole Kretz-RemyFrance Villeurbanne Université Claude Bernard Lyon IOur group is interested in cell response to protein aggregation stresses. We have shown that upon protein aggregation stresses, NFkB transcription factor is activated and in turn induces autophagy, which participates in the clearance of protein aggregates accumulated in the cell.
WG1Catalina Ribas Spain Madrid Universidad Autónoma de MadridOur laboratory is investigating key nodes in signalling networks involved in prevalent age-related pathologies such as metabolic/cardiovascular diseases and cancer.
WG1/WG2/WG4Catalina Ribas Spain Madrid Universidad Autónoma de MadridOur laboratory is investigating key nodes in signalling networks involved in prevalent age-related pathologies such as metabolic/cardiovascular diseases and cancer.
WG4Caty CasasSpainBarcelonaUniversitat Autònoma de BarcelonaChairEndogenous mechanisms in retrograde motoneurodegeneration and axonal damage.
WG3Cecilia GotorSpainSevillaCSIC Institut de Bioquímica Vegetal y FotosíntesisArabidopsis, Cysteine, Sulfide, Plant Stress, Proteomic.
WG5Cecilia Marelli France Montpellier CHRU Gui de ChauliacAggregation-directed peptide therapy for Huntington's disease; stimulation of autophagy to eliminate free polyQ huntingtin protein
WG4Chantal M.BoulangerFranceParisINSERMEndothelial autophagy, senescence, cardiovascular diseases, inflammation, apoptosis, atherosclerosis, endothelial shear stress, endothelial function.
WG1Christian BehrendsGermanyFrankfurtGoethe University FrankfurtMC T / SC VL1) Role of the family of human ATG8 proteins in autophagy and beyond. 2) Crosstalk between autophagy and the ubiquitin system. 3) Embedding of autophagy within the cellular endomembrane and trafficking system. 4) Upstream regulation of autophagy (mTOR signalling).
WG4Christine ConnollyIrelandDublinCentre for bionano interactions
WG4Christophe ViretFranceLyonINSERMAU-utophagy in infection and Crohn
WG5Christophe BautersFranceLille CedexUniversité Lille Nord de FranceTranslational research in heart failure.
WG2Clara MarquinaSpainZaragozaCSIC-Universidad de ZaragozaNanotechnology & Autophagy: Influence of different types of nanomaterials (nanoparticles etc) on inducing autophagy. Characterization by nanotechnology tools (Dual Beam 3 Nova 200, advanced TEM techniques etc.) of cells after induced autophagy. Magnetic hyperthermia as trigger mechanism of autophagy.
WG1Clarisse Berlioz-TorrentFranceParisINSERMHIV, autophagy, non-canonical role of ATG proteins, LAP, selective autophagy, restriction factor, innate immunity.
WG1ClaudineKraftAustriaVienneUniversity of VienneSignalling and molecular steps leading to autophagosome formation.
WG1Covadonga AlonsoSpainMadridInstituto Nacional de Invesigación y Tecnologia Agraria y AlimentariaStudying the interface between endocytosis and autophagy and its relevance in the innate immunity against viruses. It has shown that interferon-induced proteins, which can inhibit the entry by endocytosis of several viruses are expressed in amphisomes. Using a double stranded DNA virus as a model, are investigated new targets for antivirals. Also, working in biofunctionalization of nanoparticles with virus-derived sequences in collaboration with Dr. Jesus M. de la Fuente group. Studying biocompatibility and toxicity of compounds and their impact in autophagy.
WG4Cécile VindisFranceToulouseINSERMMC TExploring the role of mitophagy in atherosclerosis as a new target for plaque stabilization.
WG4Céline GongoraFranceMontpellierIRCM, Institut de Recherche en Cancérologie de Montpellier; INSERMRole of autophagy in drug resistance in cancer
WG3Céline Masclaux-Daubresse FranceVersaillesInstitut National de recherche AgronomiqueAbiotic stress (N, S limitations), Nutrient recycling, Nitrogen remobilisation, Leaf senescence, Metabolism, 15N tracing.
Dan LindholmFinlandHelsinkiUniversity of HelsinkiMC TSignaling Mechanisms and Organelle Dysfunctions in the regulation of Cell Death in neurons and in Neurodegenerative Diseases. Interested in signaling mechanisms for cell death in neurons and the role of cell death proteins, including the Inhibitor of Apoptosis Proteins (IAPs) in the control of neurodegeneration, in excitotoxic brain damage and in oxidative stress in the brain. Particular focus is on the role of mitochondria and endoplasmic reticulum (ER) stress in disease pathogenesis in neurological disorders, such as in amyotrophic lateral sclerosis (ALS) and Huntington´s disease (HD). Studying neuroinflammation and the roles played by peroxisome proliferator-activated receptor-gamma coactivators (PGC-1) and nuclear receptors in the regulation of cell viability and mitochondrial metabolism in neurons.
WG4/WG5Dan GrandérSwedenStockholmKaolinska InstitutRole in cancer and in sensitivity/resistance to anti-cancer therapy, screening of all anti-cancer drugs for autophagy induction, non-coding RNA in autophagy, biomarkers for autophagy in patients with cancer, development of novel anti-autophagy therapy.
WG4DanielRuiz-MolinaSpainBarcelonaCSIC Institut Català de Nanociència i Nanotecnologia
WG2/WG3Daniel HofiusSwedenUppsalaSwedish University of Agricultural Sciences (SLU)Plant-pathogen interactions, innate immunity; programmed cell death; host and pathogen targets of selective autophagy; viral pathogenesis and antiviral immunity; membrane trafficking; steroid signalling; epigenetic regulation; crosstalk with proteasome, stress and pathogen resistance in crop plants, plant biotechnology, translational and cross-kingdom approaches.
WG5Daria Ler Bosnia and HerzegovinaSarajevoPZU "Moja Klinika"MC TIdentifying risk markers and elucidating pathways responsible for breast cancer cell proliferation is important for the improvement of the risk classification in patients as well as discovery of therapeutic targets. Currently, MACC1 protein expression studies in clinical-pathologically characterized breast cancer samples was evaluated only by immunohistochemistry and showed significant MACC1 expression associated with clinical stage and lymph node metastasis. We aimed to investigate potential role of MACC1 as an effective therapeutic target and to elucidate the possible role of MACC1 in breast cancer metastasis. Taken together, MACC1 harbors a great potential to be used in clinics as a prognostic marker for the identification of high-risk patients and could be used to predict cancer recurrence and therapy response.
David ProusSpainBarcelonaProus Institut for Biomedical Research
WG4David RubinszteinUnited KingdomCambridgeUniversity of CambridgeBasic autophagy biology, Drug discovery, Translation.
WG5Delia GolettiItalyRomaNational institut for Infectious Diseases "Lazzaro Spallanzani" MC Simpact of autophagy on M. tuberculosis.
WG1/WG4Devrim GozuacikTurkeyTuzlaSabanci UniversityMC TMammalian autophagy basic mechanisms. Autophagy regulating new proteins and pathways microRNA regulation of autophagy. Role of autophagy abnormalities in diseases (cancer, neurodegenerative diseases, stroke). Manipulation of autophagy for disease treatment. Use of nano particles as autophagy drug carriers. Innovative medical device/tool development and autophagy.
WG5DiegoTosiFranceMontpellierICMImplementation of early clinical trials in cancer patients.
WG4DiegoRuano CaballeroSpainSevillaUniversidad de SevillaBasic mechanisms. Age-related modifications. Role on neurodegeneration and cancer. Cross-talk Autophagy/Proteasomal suystem. ER-stress-UPR-Autophagy.
WG1Eeva-Liisa EskelinenFinlandHelsinkiUniversity of HelsinkiMC THigh-resolution 3D imaging of forming autophagosomes and role of the small GTPase RAB24 in autophagy.
WG1Elah Pick Israel Tivon University of HaifaMC TActivation and activity of the COP9 signalosome (CSN); CRLs activity; developing CSN readout assay; NEDDylation/deneddylation; The CSN in stress, cancer and neurodegeneration. The CSN/NEDD8 axis upon oxidative stress. Regulation of sterol production and membrane fluidity by the CSN. Regulation of Autophagy by the CSN.
WG1/WG4Elżbieta KaniaPolandWarsawKU LeuvenCalcium signaling and metabolic pathways during autophagy in cancer and neurodegenerative disorders.
WG5Enzo EmanueleItalyRobbio2 E SCIENCEI work on the application of autophagy in skincare products, as well as on autophagy markers in longeve individuals.
WG3Erika IsonoGermanyFreisingTechnische Universität MünichIntracellular trafficking, endocytosis, Autophagy, Biochemistry, Cell biology.
WG1Esther Dalfó Spain Barcelona Universitat Autònoma de Barcelonafunction and the metabolic influence in the regulation of neurodegenerative
WG4Eva ZerovnikSloveniaLjubljanaInstitut Jozef StefanMC TTo get to know the molecular basis of neurodegenerative diseases, our lab is interested in cellular consequences of protein aggregation, such as recruitment of chaperones and autophagy. We concentrate on stefin B from the family of cystatins. Other processes of interest are aggresome formation, lysosomal and mitochondrial pathways of cell death and innate immune response.
Eva SjøttemNorwayTromsøUniversity of TromsøMC S
WG1/WG4/WG5Fabio PennaItalyTorinoUniversity of TorinoCancer cachexia, skeletal muscle, wasting, hypercabolism, mitochondria.
WG4Fatima Mechta-Grigoriou FranceParisInstitut CurieRole of autophagy in triple-negative breast cancers.
WG4Felipe X.Pimentel-MuiñosSpainSalamancaCentro de Investigación del Cáncer. Universidad Salamanca. CSICMolecular mechanisms involved in atypical autophagy against single membrane subcellular structures. Involvement of Atg16L1 in autophagy against infectious agents (xenophagy). Molecular bases of Crohn's disease.
WG3Fernanda Suárez MarínSpainMálagaUniversidad de MálagaProgrammed cell death, autophagy, metacaspase, plant embryo development.
WG2Fernando Novio VázquezSpainBarcelonaCSIC Institut Català de Nanociència i nanotecnologiaDesign, synthesis and characterization of nanoconstrucs as nanocontainers for different drugs and active species. Interest in the modulation of macroautophagy-lysosomal system (MALS) disorders for the treating of different diseases using nanoparticles.
WG4Filippo BertoliIrelandDublinCBNI, University College Dublin
WG4Florence PinetFranceLilleINSERMMC S1) Cardiovascular diseases, mainly heart failure. 2) Mechanisms of autophagy in link with our proteomic data sets obtained from human cohorts of patients and experimental animal models of heart fialure. 3) Translational research with availility oh human samples dedicated to our reaserch project. 4) Close link with clinicians (cardiologists, vascular surgeons)
WG1/WG2Florian GruberAustriaVienneMedical University of ViennaMC SThe main line of investigation is the generation, biological activities and degradation of oxidized lipids. Oxidized lipids are emerging as potent signaling mediators in the biology of aging, stress and inflammation of the skin. Oxidative stress is highly relevant to the biology of the skin as it is the organ most exposed to environmental stressors like ultraviolet light. For tath reason, the principal researh is in the interaction of oxidized lipids with the cellular stress response machineries, e.g. the Nrf2 response and autophagy.
WG1Francesca DemarchiItaly Trieste Laboratorio Nazionale Consorzio Interuniversitario Biotecnologie (CIB)My current project aims to study the molecular intersection between autophagy, the ubiquitin-proteasome system and the calpain/calpastatin system in the context of tumor biology and in prospective of the design of novel therapeutic strategies against autophagy-dependent tumors.
WG4/WG5Francesco CecconiDenmarkCopenhagenKraeftens BekaempelseMC SWorking on the elucidation of the upstream autophagy regulation pathways, focussing on protein post-translational modifications (phosphorylation, sumoylation, ubiquitylation) and autophagy complexes' formation. In cancer, it is testing a set of Ambra1- (or Ambra1 cofactors, such as ULK1, TRAF6, DLC1 or PP2A) interfering small peptides for their ability to regulate autophagy in tumor-model cell lines of the lung, breast and melanoma. Also, it is producing autophagy-related mouse systems to test compunds in vivo.
WG3Francisca SevillaSpainMurciaCSIC Centro de Edafología y Biología Aplicada del Segura Arabidopsis, Pisum, redox proteins, mitochondria, proteomic, Plant stress, developement.
WG1/WG4Francisco WandosellSpainMadridCSIC Centro Biologiía Molecular Severo OchoaNeurodegeneration, Neuritogenesis , Neuronal morphogenesis, Alzheimer, Ischemia, Neuronal and Glial signalling.
WG1/WG2Frank LafontFranceLilleCNRS- (UMR8204)MC S / WG2 VLHost-pathogen interaction, cellular microbiology, membrane traffic, biophysics, imaging technologies, nanotechnologies.
WG4Frank Lezoualc'hFranceToulouseINSERMTo study new signaling pathways induced by adrenergic stimulation and involved in Aging and the development of Heart Failure. Our major goal is to better understand how those signaling pathways (i.e cAMP-Epac, monoamine oxidase-A) interfere with autophagy to regulate cardiomyocyte fate (cell death, hypertrophy, senescence) in the heart. By improving autophagy, we aim at counteracting the deleterious mechanisms associated with cardiac dysfunction such as cardiomyocyte death and mitochondrial damage
WG3Frantisek BaluskaGermanyBonnUniversity of Bonn- IZMBCytoskeleton, Signaling, Endocytosis, Myotubularins, Root Cells, Imaging.
François IchasFrancePessacFluofarma
WG1/WG4Fulvio Reggiori NetherlandsGroningenUniversity of Groningen, University Medical Center GroningenMC TStudy of the regulation and mechanism of autophagy using yeast as a model system. Study the role of autophagy during viral infections.
WG1Félix M. GoniSpainBilbaoUniversidad del País VascoReconstitution of autophagosomal growth from defined components (pure human proteins and lipids); molecular interactions between autophagy-related proteins and membranes.
WG1/WG4Gabor JuhaszHungaryBudapestEOTVOS Lorand UniversityMC TRoles and molecular mechanisms of autophagy in Drosophila.
WG1Gabor Banhegyi Hungary Budapest Semmelweis UniversityInvestigation of the role of autophagy in the intermediary metabolism with special emphasis on glycogenolysis. Glycophagy under normal conditions and in glycogen storage diseases. Effects of autophagy modulating agents on carbohydrate metabolism.
WG1Gian Maria FimiaItalyRomaNational institut for Infectious Diseases "Lazzaro Spallanzani" MC SRegulation of autophagy induction; Crosstalk between autophagy and the ubiquitin proteasome system; Role of autophagy in infectious diseases (HCV, HIV, MTB).
WG1Giulia Riparini Italy Urbania University of Urbino Carlo BoAutophagy and endoplasmic reticulum stress in neurodegeneration and neuroprotection after perinatal brain damage
WG1Giuseppe BuonocoreItalySienaUniversity of SienaRole of authophagy in the newborn.
WG2Giuseppe MaulucciItalyRomaUniversità Cattolica del Sacro CuoreWorking in the field of functional imaging, on the relationship between redox state and the physical state of biomembranes mediated by lipid peroxidation products. Recently developedment of a method of confocal analysis that allow the quantification of the autophagic flux.
WG4Guido KroemerFranceParisINSERMStudying pharmacological, genetic, nutritional or behavioral interventions that induce autophagy and that may have positive effects on normal or pathological aging, as well as several major diseases (cancer, neurodegeneration) and the most frequent "rare" diseases (cystic fibrosis and Wilson disease).
WG1/WG2/WG4/WG5Guillermo Velasco DíezSpainMadridUniversidad Computense de MadridMC S / WG4 LRole of autophagy in cancer, sphingolipids, autophagy-mediated cancer cell death, autophagy signalling.
WG3Hadas
Zehavi Israel Rehovot Weizzmann Institute of Science"My work is mainly focused on a plant-specific ATG8-binding
cargo receptor (ATI1) that is induced under stress and involved in the recycling of
chloroplast proteins and possibly in ER to vacuole trafficking. ATI1 represents an interes ng
path of autophagy, as it is ini ally associated with vesicles that defer from classic
autophagosomes, but clearly requires ATG8 and the autophagic machinery to get to the
vacuole. We are aiming to elucidate its physiological role under normal growth condi ons
and under stress, as well as its rela on to the autophagy machinery and its trafficking to
the vacuole."
WG4Hang NguyenFranceClermont-ferrandINSERMTo investigate the role of autophagy in host responses to infection with bacteria associated to Crohn's disease.
WG4Hans-Uwe SimonSwitzerlandBernUniversity of BernTo determine the role of autophagy in the pathogenesis of inflammatory diseases and cancer.
WG1Harald Wodrich France Bordeaux Université de Bordeaux"My group is interested in how viruses
overcome intrinsic immunity mechanisms during entry. In this respect we have very
nice ongoing work demonstra ng how membrane ly c adenoviruses elicit and limit
membrane damage induced selec ve autophagy. I am also a cofounder of the Club
Bordelais d'Autophagy (CAB), which is the local organizing commiFee for this years
annual French Autophagy mee ng (CFATG) in Bordeaux."
WG4/WG5Heinz JungbluthUnited KingdomLondonKIng's College LondonMC SPeadiatry
Helena L. A. VieiraPortugalLisboaCEDOC, Facultdade de Ciencias Medicas Universidad Nova de LisboaMC TMitophagy related to: Mitochondrial quality control, Mitochondrial turnover, metabolism modulation and cytoprotection. Role of mitophagy in chronic and acute neurodegeneration, such as cerebral ischemia and repercussion. We are interested in understanding the molecular mechanisms underlying mitophagy and in particular mitophagy in response to stress, namely metabolic and inflammatory responses following ischemia.
WG4Helga OgmundsdottirIcelandReykjavikUniversity of IcelandMC TInterested in various aspects of the cell biology of breast cancer, including cytogenetics of breast cancer. Also molecular changes in mucosal lesions in the mouth and oral cancer. Furthermore, projects linking the study of immunology and malignancy, studying the genetic and biological basis of B-cell-derived malignancies. In a long-standing collaboration with the Faculty of Pharmaceutical Sciences the effects of lichen-derived compounds on cancer cells have been investigated. Biobank-based research on cancer causes in international collaborations. Finally, a small project on the effect of loss of the thymus during cardiac surgery in infancy on T-cell function.
WG1/WG3Henri BatokoBelgiumLouvain-la-NeuveUniversité catholique de LouvainMC T / WG3 LUnderstand the role, molecular mechanism and regulation of selective autophagy during abiotic stress in the plant cell.
WG1/WG4Henrique GiraoPortugalCoimbraFaculty of Medicine University of Coimbra-IBILIMC TWorking on the molecular mechanisms involved in ubiquitin-dependent autophagy degradation of membrane proteins; cross talk endocytosis - autophagy; autophagy in heart in health and disease; autophagosome biogenesis.
WG1/WG2/WG4/WG5Ioannis TrougakosGreeceAthensNational & Kapodistrian University of Athens,MC SMCAC focuses on proteome stability alterations during ageing and in age‐related diseases, as well as in the discovery of natural compounds that reduce proteome aggregation and prolong proteome stability and longevity at either cell‐based and/or at in vivo experimental models.
WG1Ioannis P.Nezis UK Coventry University of WarwickMolecular mechanisms of selec6ve autophagy in health and disease
WG4Iraide AllozaSpainBilbaoUniversidad del País Vasco Autophagy Biomarkers in Aterosclerosis
WG4Isabelle VergneFranceToulousePBS-CNRSMC SThe primary objective is to decode the regulation and the role of autophagy in myocbacterial infections, such as Tuberculosis, in order to propose novel vaccines and therapeutics based on autophagy.
WG1Ivan DikicGermanyFrankfurtGoethe University FrankfurtMolecular characterisation of autophagy pathway. selective autophagy receptors and adaptors.
WG1/WG4IvanaNovak NakirCroatiaSplitSchool of Medicine, University of SplitMC T
WG1James MurrayIrelandDublinTrinity College DublinMC T / TKC LMechanisms of autophagy regulation and control through reversible lipid and protein phosphorylation; enzymology, signalling kinases and cell ageing and ageing-related diseases.
WG1Jan B. ParysBelgiumLeuvenDept. Cellular and Molecular Medicine & Leuven Kanker InstituutInvestigation of the role and the targets of Ca2+ intracellularly released by the endoplasmic reticulum and/or the lysosomes in the regulation of autophagy.
WG1Jan MartinecCzech RepublicPragueThe Czech Academy of SciencesMC TFocused to unravelling of molecular mechanism of lipids and lipid-metabolizing enzymes involvement in plant autophagy induced by stress conditions
WG1Jason KingUnited KingdomSheffieldUniversity of SheffieldUnderstanding molecular mechanisms of autophagy, and its regulation.
WG4Javier Díaz-NidoSpainMadridUniversidad Autónoma de MadridNeurodegeneration. Mitophagy. Friedreich's ataxia.
WG1Jelena StankovicSerbiaBelgradeUniversity of BelgradeTesting new compounds, their anti-proliferative capacity and mechanisms involved in this process
WG4Jelena DinicSerbiaBelgradeInstitute for Biological Research "Sinisa Stankovic"MC TTargeting multidrug resistance (MDR) in cancer, mainly the evaluation of new autophagy modulators and inhibitors of P-glycoprotein function as anticancer drug candidates. Special attention is given to autophagy as one of the mechanisms of MDR, and the potential solutions for overcoming of this phenomenon. We utilize MDR human and animal cell lines as models for studying the anticancer effects and the mechanisms of action in wide range of new natural, synthetic and semi-synthetic agents.
WG1/WG3Jerome JoubèsFranceVillenave d'OrnonUniversité Bordeaux SegalenIdentification of the lipids associated with autophagy and characterization of the molecular mechanisms controlling their mobilization and their functions in plant stress responses.
WG5Jessica MartinssonSwedenHuddingeSprint BioscienceIdentifying autophagy inhibitors targeting Vps34 as cancer treatment. Program currently in lead optimization after a successful proof-of-principle study in vivo.
WG2Jesús M de la FuenteSpainZaragozaCSIC Instituto de Ciencia de Materiales de AragónMC T / TKC VLStudy of nanoparticle-cell interactions, study of endocytosis mechanisms, photothermal Therapy, Magnetic Hyperthermia. Funcionalización de superficies para el desarrollo de procesos de adhesión celular y reconocimiento molecular, y por otro lado, la preparación, caracterización y biofuncionalización de nanopartículas metálicas para su empleo en biosensores y terapia tumoral. La modificación química de la superficie de las nanopartículas o de las diferentes superficies, así como la modificación de las proteínas o carbohidratos a unir es un requisito indispensable para una biofuncionalización adecuada de estos materiales para su uso en el desarrollo de nanobiosensores. A pesar de tener una amplia experiencia en la preparación de estos materiales, es en el ámbito de su funcionalización con moléculas de interés biológico (enzimas, anticuerpos, sondas de ADN, etc) donde se centra nuestra investigación.
WG4Jesús RuberteSpainBarcelonaUniversitat Autònoma de BarcelonaStudy the role of autophagy during aging and disease in retinal blood vessels
Joan BallesterosSpainVivia Biotech Sl
WG1Joanna KamińskaPolandWarsawInstitute of Biochemistry and Biophysics PASMC S
WG1Joern DengjelGermanyFreiburgUniversity of FreiburgAutophagosome, signaling, proteomics, protein turnover, mitophagy.
WG1Jon LaneUnited KingdomBristolUniversity of BristolMC T / WG1 LMolecular regulation of autophagosome assembly; ATG4 proteins; erythropoiesis; neurodegeneration; iPSC.
WG1Jordi Alcaraz Spain Barcelona Universitat de BarcelonaStudying the role of tumor associated fibroblasts (TAFS) in lung cancer progression
WG1/WG2/WG5Jordi Alcaraz Spain Barcelona Universitat de BarcelonaStudying the role of tumor associated fibroblasts (TAFS) in lung cancer progression
WG1/WG2/WG5Jordi
Alcaraz Spain Barcelona Universitat de BarcelonaStudying the role of tumor associated fibroblasts (TAFS) in lung cancer progression
WG4JosefinaCasas BrugulatSpainBarcelonaCSICLipids. Lipidomics. Design, synthesis and evaluation of inducers/inhibitors of autophagy. Development of high throughput screening methods.
WG1/WG5José A. Sánchez AlcázarSpainSevillaUniversidad Pablo de OlavideMitophagy
WG4José M.FuentesSpainCáceresUniversidad de ExtremaduraAutophagy and Parkinson's disease. Role of PARK genes and environmental factors.
WG4José M.García FernándezSpainCartujaCSIC Instituto de Investigaciones QuímicasDesign of molecules interfering with lysosomal glycosidases involved in metabolic disorders implying autophagy deregulation. Development of pharmacological chaperones and nanodevices for the treatment of lysosomal storage disorders (Gaucher, Fabry, GM1 gangliosidosis, Tay-Sachs). Effect of pharmacological chaperones in autophagy and implementation of chaperone therapies and combined therapies.
WG4José M.LizcanoSpainBarcelonaUniversitat Autònoma de BarcelonaDissection of new signaling pathways in cancer and developing new antitumor drugs.
WGJosé M.Jerez AragonésSpainMálagaUniversidad de MálagaDetecting autophagy prognostic signature in cancer.
WG1José-Luis CrespoSpainSevillaCSICRedox regulation of autophagy by stress and chloroplast damage in photosynthetic eukaryotes using the unicellular green alga Chlamydomonas reinhardtii as model system.
WG2José-María Sánchez-PuellesSpainMadridCSICTarget validation for drug discovery, autophagy & aging.
WG5JuanSepúlveda SánchezSpainMadridHospital Universitario 12 de OctubreClinical trials for patients with cerebral tumors.
WG4JuanIovannaFranceMarseilleINSERMTC SAPancreatic cancer.
WG5Juan A. G.RaneaSpainMálagaUniversidad de MálagaBioinformatics and biology network associations.
WG4Julia LorenzoSpainBarcelonaUniversitat Autònoma de BarcelonaBioengineering
WG4Julien PuyalSwitzerlandLausanneUniversity of Lausanne,Department of Fundamental Neurosciences, Puyal- Truttmann LabMC SNeuroprotection ,Cerebral hypoxia-ischemia, excitotoxicity, neuronal death
WG4Kathrin PallaufGermanyKielInstitute of Human Nutrition and Food Science (University of Kiel)Studying the impact of potential autophagy-inducing agents (e.g. resveratrol) found in dietary plants on ageing-related processes.
WG4Kenneth A. DawsonIrelandDublinUniversity college DublinNanomaterial interactions with organisms.
WG4Kevin RyanUnited KingdomGlasgowCancer Research UK Beatson InstitutRole of autophagy in cell death and cancer.
WG1Krassimira Todorova-HayrabedyanBulgariaSofiaBulgarian Academy of SciencesMC SEffect of micro-RNAs (hsa-miR-204) on autophagy modulation in prostate cancer
WG1Lenka GemperlováCzech RepublicPragueInstitute of Experimental BotanyMC SThe first area concerns plant developmental processes studied especially on the system of coniferous somatic embryogenesis. Since autophagy is an integral part of the suspensor cell death in plant embryogenesis, we plan to study in details the early somatic embryo development phase in gymnosperms. The second part includes the effect of polyamines on the cell growth, plant cell cycle and plant responses to abiotic stresses
WG4Leonidas StefanisGreeceAthensBiomedical Research Fondation Of the Academy of AthensMC TDeciphering the involvement of autophagic pathways in neurodegenerative diseases, in particular Parkinson's Disease and related synucleinopathies; using this knowledge to devise novel therapeutic strategies based on modulation of autophagy, and in particular Chaperone-Mediated Autophagy (CMA).
WG1/WG4Leopold Eckhart AustriaViennaMedical University of ViennaMC TAutophagy in epithelial cells.
WG1Lisa Frankel Denmark Brønshøj University of CopenhagenInterconnection between RNA and autophagy. In particular, working with RNA binding proteins that impact on the autophagy signalling pathway.
WG1Lucie Fischerová Czech RepublicPragueInstitute of Experimental BotanyMolecular characterization of plant polyamine metabolism. The connection of polyamines and autophagy studied in the model system of coniferous somatic embryogenesis.
WG1Ludwig Eichinger Germany Köln University of Cologne"Our main research interest is the analysis of the molecular mechanism of autophagy in
D. discoideum. In particular, we are interested in the link between autophagy and the
proteasome, the role of autophagy in host-pathogen interactions and in non-autophagic
functions of core autophagy proteins."
WG3Luisa M. SandalioSpainGranadaConsejo Superior de Investigaciones cientificas. Estación Esperimental del ZaidinPeroxisomes, biotic and abiotic stress, imaging, reactice oxygen and nitrogen species.
WG3M. Gonzalo Claros DíazSpainMálagaUniversidad de MálagaDetemine which biomarkers and genes are involved, and how are involved, in autophagy.
WG2M. Ricardo Ibarra GarcíaSpainZaragozaUniversidad de ZaragozaInfluence of different types of nanomaterials (nanoparticles etc) on inducing autophagy. Characterization by nanotechnology tools (Dual Beam 3 Nova 200, advanced TEM techniques etc.) of cells after induced autophagy. Magnetic hyperthermia as trigger mechanism of autophagy.
WG4Marcello PintiItalyModenaUniversita Di Modena e Reggio EmiliaEffects of antiretroviral drugs used in HIV treatment on autophagy and mitophagy, particularly in adipocytes.
WG4Marco SandriItalyPadovaUniversity Of Padova-Venetian Institut of Molecular MedicineDefining the role of autophagy in acquired and inherited cardiac and skeletal muscle diseases.
WG1Margret OgmundsdottirIcelandReykjavikUniversity of IcelandMC T
WG4/WG5Maria XilouriGreeceAthensBiomedical Research Foundation of the Academy of AthensMC SPathogenesis of neurodegenerative diseases with an emphasis on the interrelationship between aggregated-prone proteins such as alpha-synuclein, MAPT/tau or beta-amyloid, to lysosomal degradation pathways.
WG1/WG4/WG5Maria Cristina AlbertiniItalyUrbinoUniversity Of Urbino "Carlo Bo"MicroRNAs involved in the epigenetic regulation of autophagy.
WG4Mario ChiarielloItalySienaConsiglio Nazionale Delle RicercheRegulation of autophagy by MAP kinase.
WG4Mario CorderoSpainSevillaUniversidad de SevillaAutophagy in aging and rare diseases.
WG4/WG5Mario P.TschanSwitzerlandBernUniversity of BernMC TCell Differentiation, physiology an dynamics.
WG4Marja JäätteläDenmarkCopenhagenDanish Cancer SocietyMC TMolecular mechanisms of autophagy, focus on cancer, signalling pathways and lipids.
WG4Markus RehmGermanyStuttgartUniversity of StuttgartFunctional, mechanistic and kinetic understanding at the level of signaling systems; Identification of combinatorial systems biomarkers and development of innovative stratification tools.
WG2/WG4/WG5Marta Martínez-VicenteSpainBarcelonaVall d'Hebron Institut de RecercaMC SNeurodegeneration, Parkinson, Huntington, therapy, nanotechnology.
WG4Martine Biard-PiechaczykFranceMontpellierCentre d’études d’agents Pathogènes et Biotechnologies pour la SantéAutophagy during viral infections, mainly HIV-1 infection. The aim is to better understand the interactions between HIV-1 and autophagy in critical immune cells of the host in order to open new avenues for therapeutic and prophylactic strategies.
WG5María MoránSpainMadridInstituto de investigación Hospital 12 de OctubreMC T / WG5 LMitochondrial diseases, autophagy modulation, therapy, muscle wasting, neurodegeneration.
WG1/WG5María SoengasSpainMadridSpanish National Research CentreWG5 SAMolecular basis of melanoma progression and response to therapy.
WG4María Luz Martínez ChantarSpainDerioCIC bioGUNEAutophagy in fatty liver disease.
WG4Mathias FaureFranceLyonINSERM, CNRS - Université Lyon MC S / WG4 VLFunction and regulation of autophagy in infections and immunity.
WG4Matthew GeggUnited KingdomLondonUniversity College LondonUnderstanding how impairment of autophagy-lysosome pathway contributes to Parkinson's disease pathogenesis.
WG2Mattia MoriItalyRomaIstituto Italiano di Tecnologia [Center for Life Nano Science]MC TDesign/optimization of small molecules; drug discovery; computational structural studies on target proteins; in silico mutagenesis; computational folding studies; natural products; medicinal chemistry.
WG5Maurizio MuscaritoliItalyRomaSapienza Università di RomaRole of autophagy in muscle wasting.
WG4Michael ThummGermanyGöttingenGeorg August universität, UniversitatsmedizinMolecular mechanism on autophagy in S.cerevisiae.
Michael GlickmanIsraelHaifaTechnion -IITMC T
WG3Michele Wolf BianchiFranceLyonCNRSAutophagosome Formation, Imaging, Abiotic Stress.
WG4Miguel Antonio López PérezSpainSantiago de CompostelaUniversidad Santiago de CompostelaAutophagy in hippotalamus control of obesity and metabolism.
WG5Miguel Ángel MartínSpainMadridServicio Madrileño de la salud. Hospital 12 de OctubreDiagnosis and physiopathology of mitochodrial diseases and other neuromuscular disorders, the role of autopahagy in these diseases.
WG5Mirza Suljagic Bosnia and HerzegovinaSarajevo International University of SarajevoMC TWe are studying  apoptosis and autophagy  regulatory proteins in Chronic myelogenous leukemia (TKI sensitive vs. TKI resistant) and Diffuse large B cell lymphoma (GC vs. ABC origin). We are targeting selected regulatory pathways with our candidate compounds  for improving current treatment options.
WG4Mograbi BahariaFranceNiceInstitut National de la sante et de la recherche médicale INSERM- IRCANAutophagy process at molecular, cellular and integrative levels in order to delineate (i) the link between autophagy, ageing and chronic diseases, (ii) the susceptibility to intrinsic (epigenetic) and extrinsic (nutrition, pollutants, carcinogens) factors and (iii) first-in-class therapies that will improve healthy ageing, slow and prevent ageing diseases (specifically cancer).
WG4/WG5Mojgan Djavaheri-MergnyFranceBordeauxINSERM- INSERM U916Deciphering the role of autophagy in cancer cells.
WG2Monika CahovaCzech RepublicPragueInsititut For Clinical and Experiental Medicine1) the evolution of mitochondrial changes in pancreatic β-cells in different experimental models of type-2 diabetes, with respect to the alterations in mitophagy. 2) the role of (dys)regulation of autophagy in the development of type-2 diabetes-related metabolic disorders, particularly liver steatosis.
WG3Morten PetersenDenmarkCopenhagenCopenhagen University- Faculty of scienceMC SInnate immunity, autophagy, MAP kinase signaling, development,
WG4Nadezda ApostolovaSpainValencia Universitat de ValenciaWG4 SAAutophagy related to HIV infection and antiretroviral drugs.
WG1Nadine CamougrandFranceBordeaux cedexInstitut de Biochimie et Génétique CellulairesStudy of mitophagy in the yeast Saccharomyces cerevisiae.
WG1/WG2/WG4Nektarios TavernarakisGreeceHeraklionFoundation for Research nd Technology-HellasMC TAgeing, Cell Death, Mitophagy, Neurodegeneration, Pexophagy, Stress Responses.
WG1Nicholas KtistakisUnited KingdomCambridgeBabraham InstitutMechanisms of autophagy induction; signaling during autophagy; discovery of small molecules regulating autophagy.
WG4Nicolas PalletFranceBordeaux INSERMAutophagy in kidney disease; autophagy in renal stress response; autophagy and endoplasmic reticulum stress
WG4Nicolas DeconinckBelgiumGentHôpital Universitaire des Enfants Reine FabiolaMechanisms of autophagy at play in neuromuscular disorders, in particular in COL VI myopathies.
WG2NikolaiEngedalNorwayOsloUniversity of OsloMC T / TKC VL1) Regulation of autophagy by calcium perturbation, ER stress signaling and the unfolded protein response 2) Intersections between autophagy and apoptosis 3) Specific roles and mechanisms of action of mammalian Atg8 proteins in autophagy
WG3Núria Sánchez Coll SpainBarcelonaCenter for research in agricultural GenomicsBiotic stress, Programmed cell death.
WG4Patrice AndréFranceLyonCentre International de Recherche en InfectiologieDevelopment of host-oriented antiviral molecules.
WG1/WG5Patrice CodognoFranceParisINSERMMC T / Vice ChairMembrane dynamics of autophagosomal compartment. Interplay between autophagy and the primary cilium: role in mechanical stress integration. Role of autophagy in self-renewal of cancer stem cells and their targeting in breast cancer treatment.
WG4Patricia BoyaSpainMadridCSCIMC S / SC LRole of autophagy during development and disease, focus on neurons.
WG4Patrick AubergerFranceNiceINSERMTargeting autophagy in hematopoietic malignancies and deciphering the role of autophagy in hematopoeitic cell differentiation
WG1Patrizia AgostinisBelgiumLeuvenUniversity of Leuven/KU LeuvenMC T / WG1 VLMelanomagenesis, angiogenesis, lymphangiogenesis, crosstalk cancer cell-stromal cells, mitophagy and metabolism, role of cancer cell-associated autophagy in therapy resistance, role of autophagy in immunogenic cell death and release of cytokines/chemokines.
WG4Pattingre SophieFranceMontpellierINSERM Posttranslational modifications of atg proteins and cancer.
WG5Paul HofmanFranceNiceInstitut for Recherch on Cancer and Aging, Nice (INSERM)Tumor Bank
WG5Paulina Langa Poland Gdansk Medical University of Gdansk"My primary research interests are mostly in the area of stem cells and transla onal medicine. I
am currently op mising a protocol for transplan ng in vitro cultured epidermal cells in the
treatment of chronic wounds a7er burns and diabe c ulcers."
WG4/WG5Penny LovatUnited KingdomNewcastle Upon TyneNewcastle UniversityMC TTo define and validate novel autophagy biomarkers and drug targets to aid stratified medicine and the development of more efficacious therapeutic strategies to harness autophagy modulation for the clinical benefit of cancer, in particular melanoma and SCC.
WG3Peter BozhkovSwedenUppsalaSwedish University of Agricultural Sciences (SLU)Aging, Plant development, Programmed cell death, Catabolism.
WG4Pierre-Emmanuel RautouFranceParisInserm- INSERM U970Translation. Role of autophagy in liver disorders and role of autophagy in endothelial cells.
WG3Pilar S. TestillanoSpainMadridBiological Research Center (CIB), Spanish National Research Council (CSIC)Autophagy in plant development, abiotic stress, plant programmed cell death, bioimaging, cell biology.
WG4Priault MurielFranceBordeauxCentre National de Recherche Scientifique CNRSAutophagy, cancer, trafic, mitochondria, Bcl-xL, Rab7.
WG4Pura Muñoz-CánovesSpainBarcelonaUniversitat Pompeu Fabra Understanding how autophagy is altered in aging and disease using skeletal muscle stem cells as a model system.
WG1Radostina Alexandrova BulgariaSofiaMuseum-Bulgarian Academy of Sciences (IEMPAM-BAS)MC TWorking in the field of experimental oncology and oncopharmacology. Establishment and morphological and functional characterization of model systems (primary cultures and permanent cell lines, including drug resistant cell lines), evaluation of antitumor activity of synthetic compounds and natural products and attempts to identify their molecular/cellular targets and mechanisms of action
WG4Rafael Delgado VázquezSpainMadridInstitut de Investigación Hospital 12 de OctubreHIV and Ebola models.
WG1/WG2/WG5Raphaël RodriguezFranceParisInstitut CurieIdentify small molecule regulators of autophagy.
WG4Raquel LimaPortugalPortoIPATIMUP/i3SMC SModulation of autophagy for cancer therapy
WG1/WG4Regina MenezesPortugalOeirasEstação Agronómica Nacional - Edificio iBET/ITQBMC SInterests focused on translational science mainly (1) the dissection of the molecular mechanisms underlying Islet Amyloid PolyPeptide (IAPP) cytotoxicity in DIABETES MELLITUS – type 1 and 2 as well as pancreas transplantations – and (2) the identification/deep characterization of PROTECTIVE PHYTOCHEMICALS. For that, investing huge efforts in the development of amenable disease models aiming at exploitation of new therapeutic strategies
WG1Renaud LegouisFranceSaclayCNRSUnderstand the physiological roles of autophagy in C. elegans life cycle (development and aging). Analyse the specific roles of LC3 family in autophagy mechanisms.
WG5Ricardo PereiraPortugalCoimbraCentro Hospitalar e Universitario de Coimbra
WG4RicardoSánchez-PrietoSpainAlbaceteUniversidad de castilla de la ManchaRole of autophagy in cancer therapy.
WG1Ricardo EscalanteSpainMadridCSICMechanisms of autophagy. Origin of autophagosomes. Functional and comparative Genomics using Dictyostelium discoideum and Mammalian cells as model systems in pathology to identify and characterize novel genes involved in autophagy. Function of VPS13 proteins and their role in Chorea-acanthocytosis and autophagy.
WG5Rui BaptistaPortugalCoimbraFaculty Of Medicine University of CoimbreTranslational projects that intend to investigate the role of autophagy in the maintenance of protein homeostasis in the heart.
WG1Rune MatthiesenPortugalLisboaInstitut Nacional de Saude Dr Ricardo Jorge (INSA,I.P.)Interested in exploring the use of state of art mass spectrometry in combination with transfected cell lines to study drug induced autophagy in relation to drug resistance.
WG1/WG4Rüta NavakauskienèLithuaniaVilniusVilnius UniversityMC SStudies of molecular mechanisms in normal and cancer cells to determine new possibilities of leukemia differentiation therapy. Identification of proteins that might be involved in signaling events that mediate cancer cell differentiation. Studies of autophagy and apoptosis signaling in cancer and adult stem cell models in vitro.
WG1Sascha MartensAustriaVienneUniversity of Vienne- Max F perutz LaboratoryReconstitution of selective autophagy.
WG1Sharon A. ToozeUnited KingdomLondonThe Francis Crick InstituteMC SElucidation of the molecular details of initiation and expansion of autophagosomes. Integration of the autophagic pathway with the secretory and endocytic pathways. Identification of novel regulators that control autophagy in pathological conditions.
WG4/WG5Silvia CarloniItalyUrbinoUniversity Of UrbinoRole of autophagy in neurodegeneration after neonatal brain ischemia.
WG1/WG4Simona PoloItalyMilanThe Firc Institute of Molecular OncoloyFocus on the crosstalk between autophagy and the ubiquitin. Characterization of HECW1, an E3 ligase of the Nedd4 family whose dysfunction causes impaired ubiquitination and autophagy. Interest in autophagy and in RNA metabolism, two pathways deregulated in the pathogenesis of cancer and neurodegeneration.
WG4Simone FuldaGermanyFrankfurtGoethe University FrankfurtRegulation of autophagy in cancer, therapeutic targeting of autophagy pathways.
WG4Sophie LotersztajnFranceParisINSERMAutophagy in the control of inflammation and metabolism during chronic liver diseases (non-alcoholic and alcoholic fatty liver diseases).
WG2/WG4Sophie LanoneFranceCréteilINSERMUnderstand the pulmonary effects of (manufactured) nanoparticles on autophagy pathway, and the role of autophagy in the biological response to (manufactured) nanoparticles.
WG1SorenHayrabedyanBulgariaSofiaBulgarian Academy of SciencesMC TInflammasome signalling interaction imaging and autophagy flux follow-up in Sertoli cells (http://www.nature.com/articles/srep18896) upon pro-inflammatory challenge as well as the effect of micro-RNAs (like hsa-miR-204) on autophagy modulation in prostate cancer (Wiley Molecular Carcinogenesis, 10.1002/mc.22263).
WG5Stéphane NanceyFranceInflammatory bowel diseases, especially in dissecting the immunologic mechanisms by which gut inflamation and lesions occurred using animal models of colitis and research in humans.
WG5Sylviane MullerFranceStrasbourgCNRSTC SAAutoimmunity, systemic autoimmune diseases, lupus. T cell and B cell epitopes, antigen-presenting cells, antibody-secreting cells, cytokines. Immunomodulation, altered peptide ligand of the T cell receptor. Autophagy, CMA, MIIC compartment, pharmacological regulators of autophagy, lysosomes. Therapeutic stratégies, mouse models of autoimmunity, autoantibodies to "some" structures. Patients, clinical trials.
WG4Sylvie GiuriatoFranceToulouseINSERM- Cancer Research Center ToulouseRole of autophagy in ALK positive anaplastic large cell lymphoma growth, regression and relapse.
WG3Tamar Avin-WittenbergGermanyPotsdamMax Planck GesellschaftMetabolic implications of autophagy during plant development and under environmental stress.
WG2/WG4Tassula Proikas-CezanneGermanyTubingenEberhard Karls University TuebingenMC T / WG2 LWIPI-mediated autophagy in health and disease and High throughput / content assessments and screening approaches.
WG1TeresaZoladekPolandInstitute of Biochemistry and Biophysics PASMolecular genetics and cellular biology of yeast with the focus on the role of ubiquitination of proteins and functioning of the actin cytoskeleton in autophagy and endocytosis.
WG4/WG5TeresaSardonSpainBarcelonaAnaxomics Biotech
WG1Terje JohansenNorwayTromsøUniversity of Tromsø - The Arctic University of TromsøMC SSelective autophagy studying the autophagy receptors p62/SQSTM1 and NBR1 but also components of the basal autophagy machinery, particularly the ATG8/LC3/GABARAP family members.
WG1/WG4Thierry ArnouldBelgiumNamurUniversité de Namur / University of NamurMC SStudy of mitochondrial function and dysfunction in stem cell differentiation, metabolism, cancer and bacterial infection
WG1Thierry Soldati Switzerland Geneva University of Geneva MC TThe major aim of my group is to understand the integration, the cooperation of signalling, cytoskeleton and membrane trafficking in phagocytosis and its relevance to host-pathogen interactions. To this end, we use the social amoeba Dictyostelium as a model organism as it is a professional phagocyte very similar to mammalian phagocytes of the innate immune system in morphology and behaviour, but which is genetically and biochemically tractable (Boulais et al, 2010;Cosson & Soldati, 2008).
Thierry
Soldati
Switzerland
Geneva
University of Geneva
MC S
WG3Tolga Bozkurt United KingdomLondonImperial College LondonMy group focuses on dissecting the molecular mechanisms underlying plant cell autonomous immunity and the role of endomembrane traffic in this process. We employ plant cell biology approach to study plant-pathogen interactions. More recently, our work on effector biology shed light on how plant pathogens manipulate autophagy to enable infection. This work highlighted the extensive remodeling of endomembrane compartments during plant-microbe interactions and opened up novel perspectives in understanding the role of autophagy in plant immunity. 
WG1Trond LamarkNorwayTromsøUniversity of Tromsø - The Arctic University of TromsøMC S
WG1/WG4Veronika BorutinskaiteLithuaniaVilniusVilnius UniversityMC TStudies of molecular mechanisms in normal and cancer cells to determine new possibilities of leukemia differentiation therapy. Identification of proteins that might be involved in signaling events that mediate cancer cell differentiation. Studies of autophagy and apoptosis signaling in cancer and adult stem cell models in vitro.
WG1/WG2/WG3Viktor ZarskyCzech RepublicPragueCharles UniversityWe aim to Looking into molecular details of the relation between plant exocyst complex and autophagy.
WG4/WG5Walter Balduini Italy Urbino University Of Urbin "Carlo Bo"MC T / TC LRole of autophagy in neurodegeneration after toxic insult during brain development.
WG2/WG4Wim Martinet Belgium Antwerp Department of Pharmaceutical Sciences We are mainly focusing on pharmacological modulation of autophagy in cardiovascular disease (non-clinical)
WG5Ömer Nuri PamukTurkeyEdirneTrakya UniversityMC T
WG1Þor (Thor)EysteinssonIcelandReykjavikUniversity of IcelandMC S
WG1Vladimir Trajkovic Serbia Belgrade University of BelgradeMC TRegulation and role of intracellular energy balance signalling pathways and autophagy in cancer and metabolic, neurological, and immune disorders.
WG4AlexanderPintzas Greece Athens National Hellenic Research Foundation My research interests have been in the scientific areas of Biology of Cancer and Cell Death, towards exploitation of the interplay of proliferative with apoptotic/autophagic pathways for novel cancer therapeutics and their rational combinations
WG4Giulia Riparini Italy Urbania University of Urbino Carlo BoAutophagy and endoplasmic reticulum stress in neurodegeneration and neuroprotection after perinatal brain damage
WG4Muriel Priault France Bordeaux Centre National de Recherche Scientifique CNRSAutophagy, cancer, trafic, mitochondria, Bcl-xL, Rab7.
WG4EstherDalfó Spain Barcelona Universitat Autònoma de BarcelonaConverging mechanisms between autophagy and axonal
function and the metabolic influence in the regulation of neurodegenerative
diseases
WG4Irena Audzeyenka Poland Warsaw Polish Academy of SciencesDefine the significance of autophagy for podocyte survival and function, as well as to assess the involvement of this process into pathogenesis of diabetic nephropathy.
WG4ZigaJakopinSlovenia Ljubljana University of LjubljanaMC TDesign/synthesis of ligands of pattern recognition receptors; Identification and biological evaluation of NOD1/2 receptor (ant)agonists; medicinal chemistry.
WG4Vincent LotteauFrance Lyon Centre International de Recherche en Infectiologie Development of host-oriented antiviral molecules.
WG4Ana Vanessa Oliveira Portugal Oeiras Instituto de Biologia Experimental e Tecnológica and Instituto de Tecnologia Química e Biológica (ITQB/UNL)Focused on translational science mainly biochemistry, cellular and molecular biology and its application to the field of gene therapy, development of biopolymers and diabetes. Interested in developing new disease models, including yeast models to complement tests in mammalian cells and animal models involved in the development of new therapeutical strategies.
WG4KarolinaPircs Sweden Lund Lund UniversityI am currently working on the linkage of autophagy and miRNAs in different neurodegenerative disorders like Huntington´s disease and Parkinson´s disease.
WG4IoannisTrougakos Greece Athens National & Kapodistrian University of AthensMC SMCAC focuses on proteome stability alterations during ageing and in age‐related diseases, as well as in the discovery of natural compounds that reduce proteome aggregation and prolong proteome stability and longevity at either cell‐based and/or at in vivo experimental models.
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